An Assay Method for Leukocyte Pyrogen
نویسنده
چکیده
A method for assaying leukocyte pyrogen is described which is shown to remain valid despite the presence of very large amounts of bacterial endotoxin. It uses a combination of two procedures to inactivate endotoxin: incubation in normal rabbit plasma for 24 hr at 37 degrees C, and injection into rabbits rendered refractory to endotoxin. The validity of the assay was confirmed by formal statistical methods. A simplified assay method is also described which lacks full statistical validity, but is more suitable for routine use.
منابع مشابه
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 126 شماره
صفحات -
تاریخ انتشار 1967